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Image Search Results
Journal: Memórias do Instituto Oswaldo Cruz
Article Title: Past and future of trypanosomatids high-throughput phenotypic screening
doi: 10.1590/0074-02760210402
Figure Lengend Snippet: HCS-based assays employed in trypanosomatid drug discovery
Article Snippet: , L. donovani , Laboratory strain: MHOM/SD/62/1S-cl2D , Intracellular amastigotes , None , Human acute monocytic leukemia (THP-1) cells , Number of host cells (cytotoxicity evaluation) and number of amastigotes per cell , Parasites kDNA and cell nucleus detected by DAPI. Cell boundary was delineated around the nucleus object. ,
Techniques: Infection, Immunostaining, Cytotoxicity Assay, Activity Assay, Luciferase, Proliferation Assay, Imaging, Time-Kill Assay, Derivative Assay, Expressing, Drug discovery, Staining, Labeling, SYBR Green Assay